产品货号：
Z19470
中文名称：
Kindlin 2/FERMT2抗体
英文名称：
Anti-Kindlin 2/FERMT2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Kindlin 2/FERMT2 Antibody |
| 指标别名 | Fermitin family homolog 2;FERMT2;KIND2;Kindlin 2;mig 2;MIG2;PLEKHC1;UNC112;UNC112B |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | FERMT2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Kindlin 2/FERMT2 recombinant protein (Position:M1-I650). |
| 实际分子量 | 70KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Fermitin family homolog 2 (FERMT2) also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or kindlin-2 is a protein that in humans is encoded by the FERMT2 gene.Enables several functions,including actin binding activity;phosphatidylinositol-3,4,5-trisphosphate binding activity;and type I transforming growth factor beta receptor binding activity.Involved in several processes,including cell surface receptor signaling pathway;positive regulation of cell differentiation;and positive regulation of cellular component biogenesis.Acts upstream of or within cell adhesion and protein localization to cell junction.Located in cytosol;focal adhesion;and nucleoplasm.Is extrinsic component of cytoplasmic side of plasma membrane.Part of adherens junction and plasma membrane.Biomarker of acute myeloid leukemia. |
| Uniprot ID | Q96AC1 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | FERM domain containing kindlin 2 |
| 蛋白名全称 | Fermitin family homolog 2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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